Leah E Cowen: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

The fungal Achilles’ heel: targeting Hsp90 to cripple fungal pathogens

Journal:

Current Opinion in Microbiology

Year:

2013

Language:

english

File:

PDF, 1.49 MB

english, 2013

2

Antifungal drug resistance: evolution, mechanisms and impact

Revie, Nicole M, Iyer, Kali R, Robbins, Nicole, Cowen, Leah E

Journal:

Current Opinion in Microbiology

Year:

2018

Language:

english

File:

PDF, 1.35 MB

english, 2018

3

Surviving the Heat of the Moment: A Fungal Pathogens Perspective

Leach, Michelle D., Cowen, Leah E., Heitman, Joseph

Journal:

Year:

2013

Language:

english

File:

PDF, 347 KB

english, 2013

4

Candida albicans Sfl1/Sfl2 regulatory network drives the formation of pathogenic microcolonies

McCall, Andrew D., Kumar, Rohitashw, Edgerton, Mira, Cowen, Leah E.

Journal:

Year:

2018

Language:

english

File:

PDF, 12.54 MB

english, 2018

5

Predicting the emergence of resistance to antifungal drugs

Journal:

FEMS Microbiology Letters

Year:

2001

Language:

english

File:

PDF, 532 KB

english, 2001

6

The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype

Journal:

Nature Reviews Microbiology

Year:

2008

Language:

english

File:

PDF, 1.61 MB

english, 2008

7

Hsp90 Orchestrates Temperature-Dependent Candida albicans Morphogenesis via Ras1-PKA Signaling

Rebecca S. Shapiro, Priya Uppuluri, Aimee K. Zaas, Cathy Collins, Heather Senn, John R. Perfect, Joseph Heitman, Leah E. Cowen

Journal:

Current Biology

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

8

Pho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by High Temperature or Hsp90 Compromise

Rebecca S. Shapiro, Adnane Sellam, Faiza Tebbji, Malcolm Whiteway, Andre Nantel, Leah E. Cowen

Journal:

Current Biology

Year:

2012

Language:

english

File:

PDF, 1.62 MB

english, 2012

9

Metabolic control of antifungal drug resistance

Nicole Robbins, Cathy Collins, Jess Morhayim, Leah E. Cowen

Journal:

Fungal Genetics and Biology

Year:

2010

Language:

english

File:

PDF, 838 KB

english, 2010

10

Predicting the emergence of resistance to antifungal drugs

Journal:

FEMS Microbiology Letters

Year:

2001

Language:

english

File:

PDF, 534 KB

english, 2001

11

Lysine Deacetylases Hda1 and Rpd3 Regulate Hsp90 Function thereby Governing Fungal Drug Resistance

Nicole Robbins, Michelle D. Leach, Leah E. Cowen

Journal:

Year:

2012

Language:

english

File:

PDF, 1.26 MB

english, 2012

12

Fungal Hsp90: a biological transistor that tunes cellular outputs to thermal inputs

Leach, Michelle D., Klipp, Edda, Cowen, Leah E., Brown, Alistair J. P.

Journal:

Nature Reviews Microbiology

Year:

2012

Language:

english

File:

PDF, 596 KB

english, 2012

13

Antagonistic Bacterial Interactions Help Shape Host-Symbiont Dynamics within the Fungus-Growing Ant-Microbe Mutualism

Poulsen, Michael, Erhardt, Daniel P., Molinaro, Daniel J., Lin, Ting-Li, Currie, Cameron R., Cowen, Leah

Journal:

Year:

2007

Language:

english

File:

PDF, 431 KB

english, 2007

14

Requirement for Ergosterol in V-ATPase Function Underlies Antifungal Activity of Azole Drugs

Zhang, Yong-Qiang, Gamarra, Soledad, Garcia-Effron, Guillermo, Park, Steven, Perlin, David S., Rao, Rajini, Cowen, Leah E.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.03 MB

english, 2010

15

Uncovering cellular circuitry controlling temperature-dependent fungal morphogenesis

Shapiro, Rebecca S., Cowen, Leah E.

Journal:

Year:

2012

Language:

english

File:

PDF, 343 KB

english, 2012

16

Evolution of Drug Resistance in Candida Albicans

Cowen, Leah E., Anderson, James B., Kohn, Linda M.

Journal:

Annual Review of Microbiology

Year:

2002

Language:

english

File:

PDF, 326 KB

english, 2002

17

To Sense or Die: Mechanisms of Temperature Sensing in Fungal Pathogens

Leach, Michelle D., Cowen, Leah E.

Journal:

Current Fungal Infection Reports

Year:

2014

Language:

english

File:

PDF, 292 KB

english, 2014

18

Elucidating drug resistance in human fungal pathogens

Xie, Jinglin Lucy, Polvi, Elizabeth J, Shekhar-Guturja, Tanvi, Cowen, Leah E

Journal:

Future Microbiology

Year:

2014

Language:

english

File:

PDF, 8.15 MB

english, 2014

19

A novel calcineurin-independent activity of cyclosporin A in Saccharomyces cerevisiae

Singh-Babak, Sheena D., Shekhar, Tanvi, Smith, Andrew M., Giaever, Guri, Nislow, Corey, Cowen, Leah E.

Journal:

Molecular BioSystems

Year:

2012

Language:

english

File:

PDF, 2.22 MB

english, 2012

20

Hsp90-dependent regulatory circuitry controlling temperature-dependent fungal development and virulence

O'Meara, Teresa R., Cowen, Leah E.

Journal:

Cellular Microbiology

Year:

2014

Language:

english

File:

PDF, 339 KB

english, 2014

21

Mechanisms of Antifungal Drug Resistance

Cowen, Leah E., Sanglard, Dominique, Howard, Susan J., Rogers, P. David, Perlin, David S.

Journal:

Cold Spring Harbor Perspectives in Medicine

Year:

2015

Language:

english

File:

PDF, 1.02 MB

english, 2015

22

Fitness Trade-Offs Associated with the Evolution of Resistance to Antifungal Drug Combinations

Hill, Jessica A., O’Meara, Teresa R., Cowen, Leah E.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.97 MB

english, 2015

23

Opportunistic yeast pathogens: reservoirs, virulence mechanisms, and therapeutic strategies

Polvi, Elizabeth J., Li, Xinliu, O’Meara, Teresa R., Leach, Michelle D., Cowen, Leah E.

Journal:

Cellular and Molecular Life Sciences

Year:

2015

Language:

english

File:

PDF, 699 KB

english, 2015

24

Hsp90 Governs Dispersion and Drug Resistance of Fungal Biofilms

Robbins, Nicole, Uppuluri, Priya, Nett, Jeniel, Rajendran, Ranjith, Ramage, Gordon, Lopez-Ribot, Jose L., Andes, David, Cowen, Leah E., May, Robin Charles

Journal:

Year:

2011

Language:

english

File:

PDF, 4.73 MB

english, 2011

25

Mechanisms of Candida albicans Trafficking to the Brain

Liu, Yaoping, Mittal, Rahul, Solis, Norma V., Prasadarao, Nemani V., Filler, Scott G., Cowen, Leah E.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.26 MB

english, 2011

26

PKC Signaling Regulates Drug Resistance of the Fungal Pathogen Candida albicans via Circuitry Comprised of Mkc1, Calcineurin, and Hsp90

LaFayette, Shantelle L., Collins, Cathy, Zaas, Aimee K., Schell, Wiley A., Betancourt-Quiroz, Marisol, Gunatilaka, A. A. Leslie, Perfect, John R., Cowen, Leah E., Mitchell, Aaron P.

Journal:

Year:

2010

Language:

english

File:

PDF, 3.53 MB

english, 2010

27

Genomic Transition to Pathogenicity in Chytrid Fungi

Joneson, Suzanne, Stajich, Jason E., Shiu, Shin-Han, Rosenblum, Erica Bree, Cowen, Leah E.

Journal:

Year:

2011

Language:

english

File:

PDF, 825 KB

english, 2011

28

Global analysis of fungal morphology exposes mechanisms of host cell escape

O’Meara, Teresa R., Veri, Amanda O., Ketela, Troy, Jiang, Bo, Roemer, Terry, Cowen, Leah E.

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 2.26 MB

english, 2015

29

Hsp90 Governs Echinocandin Resistance in the Pathogenic Yeast Candida albicans via Calcineurin

Singh, Sheena D., Robbins, Nicole, Zaas, Aimee K., Schell, Wiley A., Perfect, John R., Cowen, Leah E., Mitchell, Aaron P.

Journal:

Year:

2009

Language:

english

File:

PDF, 812 KB

english, 2009

30

Mapping the Hsp90 Genetic Interaction Network in Candida albicans Reveals Environmental Contingency and Rewired Circuitry

Diezmann, Stephanie, Michaut, Magali, Shapiro, Rebecca S., Bader, Gary D., Cowen, Leah E., Snyder, Michael

Journal:

Year:

2012

Language:

english

File:

PDF, 967 KB

english, 2012

31

Inhibition of Candida parapsilosis Fatty Acid Synthase (Fas2) Induces Mitochondrial Cell Death in Serum

Nguyen, Long Nam, Cesar, Gabriele Vargas, Le, Giang Thi Thu, Silver, David L., Nimrichter, Leonardo, Nosanchuk, Joshua D., Cowen, Leah E.

Journal:

Year:

2012

Language:

english

File:

PDF, 4.46 MB

english, 2012

32

Acquisition of Aneuploidy Provides Increased Fitness during the Evolution of Antifungal Drug Resistance

Selmecki, Anna M., Dulmage, Keely, Cowen, Leah E., Anderson, James B., Berman, Judith, Madhani, Hiten D.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.18 MB

english, 2009

33

Genetic and Genomic Architecture of the Evolution of Resistance to Antifungal Drug Combinations

Hill, Jessica A., Ammar, Ron, Torti, Dax, Nislow, Corey, Cowen, Leah E., Fay, Justin C.

Journal:

Year:

2013

Language:

english

File:

PDF, 3.29 MB

english, 2013

34

The Set3/Hos2 Histone Deacetylase Complex Attenuates cAMP/PKA Signaling to Regulate Morphogenesis and Virulence of Candida albicans

Hnisz, Denes, Majer, Olivia, Frohner, Ingrid E., Komnenovic, Vukoslav, Kuchler, Karl, Cowen, Leah E.

Journal:

Year:

2010

Language:

english

File:

PDF, 5.34 MB

english, 2010

35

UDP-glucose 4, 6-dehydratase Activity Plays an Important Role in Maintaining Cell Wall Integrity and Virulence of Candida albicans

Sen, Manimala, Shah, Bhavin, Rakshit, Srabanti, Singh, Vijender, Padmanabhan, Bhavna, Ponnusamy, Manikandan, Pari, Koteppa, Vishwakarma, Ram, Nandi, Dipankar, Sadhale, Parag P., Cowen, Leah E.

Journal:

Year:

2011

Language:

english

File:

PDF, 3.14 MB

english, 2011

36

A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid Homeostasis

Lissina, Elena, Young, Brian, Urbanus, Malene L., Guan, Xue Li, Lowenson, Jonathan, Hoon, Shawn, Baryshnikova, Anastasia, Riezman, Isabelle, Michaut, Magali, Riezman, Howard, Cowen, Leah E., Wenk, Mar

Journal:

Year:

2011

Language:

english

File:

PDF, 1.77 MB

english, 2011

37

Msb2 Shedding Protects Candida albicans against Antimicrobial Peptides

Szafranski-Schneider, Eva, Swidergall, Marc, Cottier, Fabien, Tielker, Denis, Román, Elvira, Pla, Jesus, Ernst, Joachim F., Cowen, Leah E.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.22 MB

english, 2012

38

Global Analysis of the Evolution and Mechanism of Echinocandin Resistance in Candida glabrata

Singh-Babak, Sheena D., Babak, Tomas, Diezmann, Stephanie, Hill, Jessica A., Xie, Jinglin Lucy, Chen, Ying-Lien, Poutanen, Susan M., Rennie, Robert P., Heitman, Joseph, Cowen, Leah E., Mitchell, Aaron

Journal:

Year:

2012

Language:

english

File:

PDF, 2.23 MB

english, 2012

39

Functional Genomic Analysis of Candida glabrata-Macrophage Interaction: Role of Chromatin Remodeling in Virulence

Rai, Maruti Nandan, Balusu, Sriram, Gorityala, Neelima, Dandu, Lakshmi, Kaur, Rupinder, Cowen, Leah E.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.79 MB

english, 2012

40

Hsp90 Orchestrates Stress Response Signaling Governing Fungal Drug Resistance

Cowen, Leah E., Madhani, Hiten D.

Journal:

Year:

2009

Language:

english

File:

PDF, 612 KB

english, 2009

41

Hsp90 Orchestrates Transcriptional Regulation by Hsf1 and Cell Wall Remodelling by MAPK Signalling during Thermal Adaptation in a Pathogenic Yeast

Leach, Michelle D., Budge, Susan, Walker, Louise, Munro, Carol, Cowen, Leah E., Brown, Alistair J. P., Andrianopoulos, Alex

Journal:

Year:

2012

Language:

english

File:

PDF, 2.55 MB

english, 2012

42

Regulatory circuitry governing morphogenesis in Saccharomyces cerevisiae and Candida albicans

Shapiro, Rebecca S., Ryan, Owen, Boone, Charles, Cowen, Leah E.

Journal:

Year:

2012

Language:

english

File:

PDF, 446 KB

english, 2012

43

Coupling temperature sensing and development

Shapiro, R.S., Cowen, Leah E.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.09 MB

english, 2010

44

Using combination therapy to thwart drug resistance

Hill, Jessica A, Cowen, Leah E

Journal:

Future Microbiology

Year:

2015

Language:

english

File:

PDF, 2.06 MB

english, 2015

45

Skin Reactions in a Subset of Patients With Stage IV Melanoma Treated With Anti–Cytotoxic T-Lymphocyte Antigen 4 Monoclonal Antibody as a Single Agent

Jaber, Samer H., Cowen, Edward W., Haworth, Leah R., Booher, Susan L., Berman, David M., Rosenberg, Steven A., Hwang, Sam T.

Journal:

Archives of Dermatology

Year:

2006

Language:

english

File:

PDF, 388 KB

english, 2006

46

Progress and prospects for targeting Hsp90 to treat fungal infections

VERI, AMANDA, COWEN, LEAH E.

Journal:

Year:

2014

Language:

english

File:

PDF, 691 KB

english, 2014

47

Beauvericin Potentiates Azole Activity via Inhibition of Multidrug Efflux, Blocks C. albicans Morphogenesis, and is Effluxed via Yor1 and Circuitry Controlled by Zcf29

Shekhar-Guturja, Tanvi, Tebung, Walters Aji, Mount, Harley, Liu, Ningning, Köhler, Julia R., Whiteway, Malcolm, Cowen, Leah E.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 5.52 MB

english, 2016

48

Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans

Leach, Michelle D., Farrer, Rhys A., Tan, Kaeling, Miao, Zhengqiang, Walker, Louise A., Cuomo, Christina A., Wheeler, Robert T., Brown, Alistair J. P., Wong, Koon Ho, Cowen, Leah E.

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 2.68 MB

english, 2016

49

Extensive Functional Redundancy in the Regulation of Candida albicans Drug Resistance and Morphogenesis by Lysine Deacetylases Hos2, Hda1, Rpd3, and Rpd31

Li, Xinliu, Robbins, Nicole, O'Meara, Teresa R., Cowen, Leah E.

Journal:

Molecular Microbiology

Year:

2016

Language:

english

File:

PDF, 4.37 MB

english, 2016

50

Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae

Anderson, James B., Sirjusingh, Caroline, Parsons, Ainslie B., Boone, Charles, Wickens, Claire, Cowen, Leah E., Kohn, Linda M.

Journal:

Year:

2003

Language:

english

File:

PDF, 222 KB

english, 2003